35 stroke victims with carotid and intracranial artery blockages were
treated with HBOT. Treatment began with an average delay of 10 weeks after
Fifteen of the 35 patients improved, both clinically and on EEG.
Holbach K.H., Wassmann H., Hoheluchter K.L., and Jain K.K. Differentiation between reversible and irreversible poststroke changes in brain tissue. Surg Neurol 7:325, 1977
It has been shown that HBO increases production of stem cells in the injured brain by as much as 8-fold. This could explain why continued benefit is seen.
Other Research Report Shows that Hyperbaric Oxygen Benefits Stroke Victims
Data were analyzed from published clinical studies on treatment of stroke patients by 11 different hyperbaric centers (a total of 265 patients). The cumulative amount of hyperbaric oxygen therapy (DHBOT) was calculated using the product of chamber oxygen pressure (ATA), times the duration of each HBOT (hours), times the total number of hyperbaric treatments. Efficacy of HBOT (EfHBOT) was computed from the number of patients in each study who showed significant clinical improvement of their neurologic status as a result of HBOT (percentage of the total number of patients who improved). The level of EfHBOT was compared with the corresponding value of DHBOT, indicating that benefit correlates directly with DHBOT. From the plot below, it can be seen that average improvement increased with each treatment and that 30 one-hour HBOT treatments would seem to correlate with optimum benefit.
Rogatsky GG, Shifrin EG, Mayevsky A. Optimal dosing as a necessary
condition for the efficacy of hyperbaric oxygen therapy in acute ischemic
stroke: a critical review. Neurol Res. 2003 Jan;25(1):95-8
HBOT Improved Stroke Residuals Even Treated Years After the Attack
Sevent-nine patients were treated with HBOT from 5 months to 10 years post stroke.
65% of those patients reported improvement in their quality of life, despite the long delay before treatment.
Neubauer RA, End E. Hyperbaric oxygenation as an adjunct therapy in strokes due to thrombosis. Stroke 11:297-300, 1980
Two Case Reports: Remarkable Improvement in Stroke Patients
1) A 66-year old man was totally incapacitated following a stroke. He required full-time nursing care. After HBOT he could once again feed himself, he regained bladder and bowel control, and he his mobility improved. SPECT (positron emission computerized tomography) brain scans showed improved function in damaged areas.
2) A 60 year-old woman suffered a stroke 13 years prior to HBOT. She was partially paralyzed on one side with speech and drooling problems. Following HBOT her speech was much better, she no longer drooled and her strength and mobility improved. SPECT (positron emission computerized tomography) brain scans showed improved function in damaged areas.
Copyright © 2012 Elmer M. Cranton, M.D., all rights reserved